Summary
Among other things, GLP (Good Laboratory Practice) requires that the accuracy and precision of analytical instruments are checked at regular intervals using Standard Operating Procedures (SOPs). The user is advised to validate the pH meter as a whole integrated measuring system, i.e. including the electrode(s) and any stirrer that may be used. The checking of the electronic and mechanical components can and should be carried out by qualified personnel from the manufacturing company as part of regular servicing. All newer Metrohm pH meters are provided with start-up test routines, which check that the instrument is functioning perfectly when it is switched on. If no error message is displayed it can be assumed that the instrument is functioning correctly. Metrohm also supplies its instruments with integrated diagnostic programs, which enable the user to check the functioning of certain components in the event of malfunctions or erratic behavior and to localize the fault. These diagnostic programs can also be included in a validation procedure.The procedure described below is meant as a guideline for setting up a Standard Operating Procedure to check your pH meter (with electrode connected). The limits specified should be regarded as examples. Depending on the requirements placed on the accuracy of the measuring system these limits may have to be redefined in the Standard Operating Procedure.
PDF] Application Bulletin
Among other things, GLP (Good Laboratory Practice) requires that the accuracy and precision of analytical instruments are checked at regular intervals using Standard Operating Procedures (SOPs). The user is advised to validate the pH meter as a whole integrated measuring system, i.e. including the electrode(s) and any stirrer that may be used. The checking of the electronic and mechanical components can and should be carried out by qualified personnel from the manufacturing company as part of regular servicing. All newer Metrohm pH meters are provided with start-up test routines, which check that the instrument is functioning perfectly when it is switched on. If no error message is displayed it can be assumed that the instrument is functioning correctly. Metrohm also supplies its instruments with integrated diagnostic programs, which enable the user to check the functioning of certain components in the event of malfunctions or erratic behavior and to localize the fault. These diagnostic programs can also be included in a validation procedure.The procedure described below is meant as a guideline for setting up a Standard Operating Procedure to check your pH meter (with electrode connected). The limits specified should be regarded as examples. Depending on the requirements placed on the accuracy of the measuring system these limits may have to be redefined in the Standard Operating Procedure.
PDF] Application Bulletin
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