Tuesday, February 17, 2009

Antimicrobial cationic peptides

A novel class of cationic peptides having antimicrobial activity is disclosed. These peptides can be encompassed by the formulas: PRETEXTREPLACED wherein: m is 1 to 5; n is 1 or 2; o is 2 to 5; r is 0 to 8; u is 0 or 1; X.sub.1 is Isoleucine, Leucine, Valine, Phenylalanine, Tyrosine, Tryptophan or Methionine; X.sub.2 represents Tryptophan or Phenylalanine X.sub.3 represents Arginine or Lysine; X.sub.4 represents Tryptophan or Lysine; and X.sub.5 represents Phenylalanine, Tryptophan, Arginine, Lysine, or Proline. The invention also provides a method of producing a cationic peptide variant having antimicrobial activity.
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FIELD OF THE INVENTION The invention relates to peptides that have antimicrobial activity.

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