A test method for the determination of the liquid efflux rate (tightness) of Metrohm Antidiffusion Tips via STAT Titration, Application Bulletin 306/e

Summary
The design of the Metrohm antidiffusion tips with thentidiffusion valve makes it possibleto do very accurate dosing. The principle is a ‘pressure valve’ which opens synchronously to the movement of the piston from the Dosing unit, depending on the pressure in
the tubing, and relocks when the pressure in the tubing drops. This principle makes sure, that the volume stream stops abrupt after stop of the piston movement and no formation of drops and no leakage of titrant occurs afterwards. If this mechanism doesn’t work properly then it is possible that after a dosing step a volume different from the documented leaks from the anti diffusion tip. This ‘leakage’ may furthermore cause a delayed stabilization of the measured signal and may hence create erroneous, inaccurate results. Metrohm recommends the use of the titrimetric volume test method described below as the Standard
Operating Procedure for validating Metrohm antidiffusion tips (6.1543.200, 6.1543.130 & 6.1543.140, each with 62726.090 antidiffusion valve).

This titrimetric volume test can be used for the following purposes:
• Quality assurance by the manufacturer
• Quality assurance of analytical or other measur-
ing systems by the user
The described method is not an official reference method.


[PDF]Application Bulletin

Catalog Metrohm, Application Note in 797

the methods described in the metrohm application bulletins and application notes are ... of course available the most important applications stripping voltammetry voltammetric ...
	[View page 7] the analysis can be started further applications with the corresponding methods are ... available in the metrohm application bulletins and application notes these ...
	[View page 15] application bulletins metrohm has published about ... 50 application bulletins describing polarographic or ... just how versatile voltammetry is application bulletin no water wastewater ... vitamin e in edible fats and oils application bulletin no metals electroplating ... in water foodstuffs and wastewater 207 application notes the application notes present ... applications in compact form for the voltammetry ... sector there are currently about 120 application notes in english these are supplied in ... methods for carrying out these applications are included in the software of the 797 ...

The role of Platinum in modern industry

Platinum plays a huge role in modern industry - notably in electrochemical and catalytic systems: this article reviews the origins, uses, and detection methods available

Platinum plays a huge role in modern industry - notably in electrochemical and catalytic systems, and is currently being used in fuel and electrolytic cells, pharmaceutical production, petro-chemistry, laboratory equipment, electrical contacts, dentistry and anti-pollution devices in the automotive and water-treatment sectors, as well as surgical and astronomical devices.

Areticles

Determination of the total base number (TBN)in petrochemical products by potentiometric HClO4 titration Metrohm AG

Determination of the total base number (TBN) in petrochemical products by potentiometric HClO4 titration

Summary
The base numbers of three different lubricating oil samples were determined. Work was carried out using different electrode systems in different solvent mixtures (glacial acetic acid/toluene and glacial acetic acid/chlorobenzene) and with different titration modes (drift and time-controlled dynamic titrations). The results obtained displayed no significant differences in their reproducibility and were all within the tolerance limits.


Articles

Determination of the total base number (TBN)in petrochemical products by potentiometric HClO4 titration Metrohm AG

Determination of the total base number (TBN) in petrochemical products by potentiometric HClO4 titration

Summary
The base numbers of three different lubricating oil samples were determined. Work was carried out using different electrode systems in different solvent mixtures (glacial acetic acid/toluene and glacial acetic acid/chlorobenzene) and with different titration modes (drift and time-controlled dynamic titrations). The results obtained displayed no significant differences in their reproducibility and were all within the tolerance limits.


Articles

Vlidation, Application Bulletin Metrohm

Validation

Article	Name
AN-H-048	Standardization of disodium dimethylglyoximate for the determination of nickel
Standardization of disodium dimethylglyoximate by thermometric titration with standard Ni(II) solution.
AN-H-042	Standardization of thiosulfate titrant for copper determinations
Standardization of thiosulfate titrant for use in the determination of copper.
AB-306	A test method for the determination of the liquid efflux rate (tightness) of Metrohm Antidiffusion Tips via STAT Titration
The design of the Metrohm antidiffusion tips with the antidiffusion valve makes it possible to carry out very accurate dosing. The principle is a ‘pressure valve’ which opens synchronously with the movement of the Dosing unit piston (i.e.when the pressure in the tubing increases) and closes when the pressure in the tubing drops. This principle ensures that the volume flow stops abruptly when piston movement stops and no drop formation or titrant leakage occurs subsequently. If this mechanism is not working properly then a volume different from that documented can leak from the antidiffusion tip after the dosing step. This ‘leakage’ may also cause a delayed stabilization of the measured signal and produce faulty and inaccurate results. Metrohm recommends the use of the titrimetric volume test method described below as the Standard Operating Procedure for validating Metrohm antidiffusion tips (6.1543.200, 6.1543.130 & 6.1543.140, each with 62726.090 Antidiffusion valve). This titrimetric volume test can be used for the following purposes: Quality assurance by the manufacturer Quality assurance of analytical or other measuring systems by the user The described method is not an official reference method.
AB-283	Validation of Metrohm burets		Validation of Metrohm burets " src="http://products.metrohm.com/getAttachment.axd?attaName=b06887ad-787c-4437-b7da-90dd9196ad22&iataName=WebLarge" border="0" width="50">
Among other things, GLP (Good Laboratory Practice) requires that the accuracy and precision of analytical instruments are checked at regular intervals using Standard Operating Procedures (SOPs). Metrohm recommends the use of the gravimetric test method described below as the Standard Operating Procedure for validating Dosing and Exchange Units. This gravimetric linearity test can be used for the following purposes: • Quality assurance by the manufacturer • Quality assurance of analytical or other measuring systems by the user The described method is not an official reference method. The metrological requirements placed on piston burets, in particular the maximum permissible measurement errors, are specified in the ISO Standards 8655-1 to 8655-6.
AB-281	Validation of the 774 Oven Sample Processor in combination with a KF Coulometer by using standard operating procedures
GLP (Good Laboratory Practice) requires, among other things, the regular checking of the accuracy and precision of analytical instruments by using standard operating procedures (= SOPs). The user is recommended to validate Metrohm instruments as a whole integral measuring system, i.e. to carry out a series of determinations with certified standards and to critically assess the results by statistical means. Checking the electronic components of measuring instruments can and ought to be carried out in the context of regular service work by technical specialists from the manufacturing company. All Metrohm instruments are provided with start-up test routines that check that the relevant components are functioning properly when the instrument is switched on. If this produces no error message then it can be assumed that the instrument is functioning perfectly. Metrohm also supplies its instruments with built-in diagnosis programs that, if faults or malfunctions should occur, permit the user to check the functioning of particular assemblies and localize the fault. These diagnosis programs can also be included in a validation method. As a guideline for drawing up a standard operating procedure for checking the complete analytical system, Metrohm recommends the procedure described in this Bulletin. The limiting values mentioned should be regarded as being proposals. Depending on your company-specific requirements for the accuracy of the measuring system these limits may need to be redefined in the standard operating procedures. Articles